The Road to El Dorado 2

The Road to El Dorado 2 was a planned sequel to the 2000 DreamWorks animated film The Road to El Dorado.

Plot
Miguel, Tulio, and Chel set off to a new adventure, rest of the plot is unknown.

Why It Was Cancelled

 * The first film bombed at the box office.
 * DreamWorks abandoned 2D traditional animation in favor of CGI animation following the box office failure of Sinbad: Legend of the Seven Seas in 2003.

Result
The film was cancelled permanently and the first film is a stand-alone film.